Visualizations of likely axon-carrying dendrites in the Layer 2/3 serial EM volume
This reconstruction was made using the synapse_visualizer.ipynb
notebook. The post-synaptic sites (on the dendrites) are shown in
red and the pre-synaptic sites (on the presumtive axon) are shown in
green for cellid 648518346349536971.
Pre- and post-synaptic sites on the axonal and dendritic processes for cellid 648518346349536971
Review of the raw EM images, the presumptive axonal process is continuous with the dendrite and does not appear to be a segmentation error.
EM view of axon-carrying dendrite for cellid 648518346349536971
This is another potential axon-carrying dendrite for cellid 648518346349536971. This is likely an L5 or L6 pyramidal neuron from a deeper layer below the Layer 2/3 volume.
Pre- and post-synaptic sites on the axonal and dendritic processes for cellid 648518346342793912
Review of the raw EM images, the presumptive axonal process is continuous with the dendrite and does not appear to be a segmentation error.
EM view of axon-carrying dendrite for cellid 648518346342793912
3D reconstruction of bipolar inhibitory neuron withaxon-carrying dendrite. Pre-synaptic sites shown in green and post-synaptic sites shown in red.
3D reconstruction of bipolar inhibitory neuron withaxon-carrying dendrite.
Neuroglancer view of bipolar neuron with an axon-carrying dendrite.
Neuroglancer view of bipolar neuron with an axon-carrying dendrite
Axon-carrying dendrites (AcD) are not uncommon in rodents, with estimated 10-21% of pyramidal neurons having AcDs. See their paper in eLife entitled Neocortical pyramidal neurons with axons emerging from dendrites are frequent in non-primates, but rare in monkey and human for more details.